By E. S. E. Hafez (auth.), Kurt Benirschke (eds.)
To many, the contents of this convention won't look applicable at a time while the minds are preoccupied with a "population explosion." To the individuals and site visitors of this convention, besides the fact that, this was once per week of interesting discussions. whereas quantitative points of reproduc tion have been touched upon, it used to be as a rule a look for an knowing of the qualitative facets of replica and its failure. in basic terms once we comprehend those extra thoroughly will it's attainable to render optimal care and feature the rules for significant inhabitants keep watch over. The convention used to be conceived in discussions on the Committee on Pathology of the nationwide Academy of Sciences, W"ashington, in 1965. It was once felt that investigators in drugs and the veterinary fields may revenue significantly from a better liaison. All too often, we paintings particularly remoted in our respective fields and, with the burgeoning details filling our journals, we've not sufficient time and rest to face again and try a comparative examine the topic of research. frequently we're not conversant in the options different disciplines use, and which shall we good hire to nice virtue. ,,yhile this is applicable to many elements of drugs, a comparative method of the research of reproductive failure appeared prime at this time.
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Additional resources for Comparative Aspects of Reproductive Failure: An International Conference at Dartmouth Medical School, Hanover, N.H.—July 25–29, 1966
Group II. Emf)ly Chorionic Vesicle . This is common and the most pathologic of all "blighted" ova. It is often intact so that the pathologist may prove to himself that th ere is no derivative of the embryonic mass or germ disk. Group 111. Chorion Contllilling, Empty Amnion. This is only slightly less pathologic than Group II. It is valid, common and often intact. Such a specimen is to be seen in Figure 10. Fig. 10. ,\ typical "blighted" or pathologic ovum of Carnegie Croup III, a chorion containing an empty amnion .
3. 4. an interest in the problem fine dissecting instruments, mostly ophthalmological a good binocular dissecting microscope a knowledge of embryologic and chorionic pathology during the first trimester when most spontaneous abortions occur 5. the willingness to spend time and "tender loving care" in evaluating the specimen and selecting proper blocks for microscopic section. Arthur T. Hertig 30 It is better to examine the specimen fresh rather than after fixation. If a physician fixes the specimen first it should be done in plenty of 10 per cent formalin within a widemouthed container.
In spite of the relative advancement of ovular development, the embryo consists only of ectoderm. Owing to the lack of chorionic cavity (segmentation cavity of blastula), there is no formation of auxiliary structures such as chorionic mesoblast, blood vessels, amnion or primary yolk sac. These structures delaminate in situ from the cytotrophoblast lining a chorionic cavity as shown by Hertig in 1935. Although this is a growing and viable ovum at present, it is destined to abort. The embryo for some days lives in a large tissue culture-like chamber with no blood supply of its own.