Cancer of the Lung: From Molecular Biology to Treatment by Alan Weitberg

By Alan Weitberg

Alan B. Weitberg, MD, and a panel of the world over well-known simple scientists and clinicians current a accomplished dialogue of lung melanoma, together with a practice-oriented overview of its analysis, overview, and therapy. The individuals supply not just an comprehensible description of its molecular origins-an crucial key to constructing destiny treatments and preventive measures-but additionally conscientiously talk about well-tested ways, in addition to those who are at the moment being evaluated for destiny use in either the laboratory and health facility. The publication additionally elucidates the production and powerful deployment of remedy directions brought via 3rd occasion payers to enhance scientific results, even whereas reducing healthcare charges.

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Extra info for Cancer of the Lung: From Molecular Biology to Treatment Guidelines (Current Clinical Oncology)

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38. Irabarren C, Tekawa IS, Sidney S, Friedman G. Effect of cigar smoking on the risk of cardiovascular disease, chronic obstructive pulmonary disease, and cancer in men. N Engl J Med 1999;340(23):1773–1780. 39. IARC Monographs on the evaluation of the carcinogenic risk of chemicals to humans. Tobacco smoking. IARC 1985;35. 40. Higgins ITT, Mahan CM, Wynder EL. Lung cancer among cigar and pipe smokers. Prev Med 1988;17:116–128. 41. Incidence of initiation of cigarette smoking—United States, 1965–1996.

SCC is often associated with squamous metaplasia of the bronchial epithelium. 2. CLINICAL FEATURES Formerly the most common type of lung carcinoma, SCC has been surpassed in frequency by adenocarcinoma (9). SCC is seen predominately in males, and cigarette smoking is considered to be the primary etiologic factor. Human papilloma virus (HPV) has been found in some cases of bronchial squamous metaplasia and SCC (10,11); however, a recent study implicated HPV in the carcinogenesis of laryngeal but not lung SCC (12).

Mortality of workers exposed to acrylonitrile. J Occup Med 1992;34(8):801–809. 137. Strother DE, Mast RW, Kraska RC, Frankos V. Acrylonitrile as a carcinogen. Research needs for better risk assessment. Ann NY Acad Sci 1988;534:169–178. 138. O’Berg MT, Chen JL, Burke CA, Walrath J, Pell S. Epidemiologic study of workers exposed to acrylonitrile: an update. J Occup Med 1985;27(11):835–840. 139. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Genetic and related effects: an updating of selected IARC monographs from volumes 1 to 42.

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