By Gustavo Maroni
Drosophila, the typical fruit fly, is the main largely studied of all organisms from the perspective of genetics and cytology. This atlas summarizes what's identified in regards to the nearly a hundred Drosophila genes for which the total nucleotide series is understood. each one access features a description of the gene's molecular association and expression, the whole nucleotide and amino acid sequences, maps of attention-grabbing buildings, highlights of useful gains and promoter regulatory areas, and chosen references to the first literature. A separate component of the atlas considers various elements of gene association as they happen within the Drosophila genome. issues coated comprise measurement correlations between quite a few genetic components, splicing signs, translation initiation indications, and codon bias. The paintings represents a brand new milestone in summarizing present details and making it simply available to geneticists and biologists.
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Extra resources for An Atlas of Drosophila Genes: Sequences and Molecular Features
And Deibler, G. E. (1975). Purified Drosophila alpha-amylase isozymes: genetical, biochemical and molecular characterization. In Isozymes: Current Topics in Biological and Medical Research, ed. L. Markert (New York, NY: Alan R. Liss), Volume 4, 585-607. Doane, W. , Treat-Clemons, L. , Gemmill, R. , Levy, J. N, Hawley, S. A, Buchberg, A. M. and Paigen, K. (1983). Genetic mechanism for tissue-specific control of alpha-amylase expression in Drosophila melanogaster. In Isozymes: Current Topics in Biological and Medical Research, eds M.
L. (1989). Alternative 5C actin transcripts are localized in different patterns during Drosophila embryogenesis. Dev. Biol. 131:345-355. -T. and Keller, E. B. (1990a). Regulatory elements mediating transcription from the Drosophila melanogaster Actin 5C proximal promoter. Mol. Cell. Biol. 10:206-216. -T. and Keller, E. B. (1990b). Positive and negative regulatory elements mediating transcription from the Drosophila melanogaster Actin 5C distal promoter. Mol. Cell. Biol. 10:6172-6180. Couderc, J.
1986). Two FIG. 1. Diagram of the organization and expression of Adh and Adh-dup Alcohol dehydrogenase: Adh, Adh-dup 39 (continued) 40 AN ATLAS OF DROSOPHILA GENES Adh SEQUENCE. Slow allele from Canton S. Accession M14802 (DROADHA). Several other alleles have been sequenced and are listed under DROADH* in GenBank. Several mutations are indicated (Benyajati et al. 1982; Martin et al. 1985; Place et al. 1987; Thatcher 1980). Indicated under the sequence in the promoter regions are binding sites for various regulatory proteins.